Transcranial pulsed magnetic field stimulation facilitates reorganization of abnormal neural circuits and corrects behavioral deficits without disrupting normal connectivity.
This study shows that PMFs can correct abnormal neuronal (nerve cell) responses, and even selectively removed axons (the long shaft of a nerve cell) that formed in areas they shouldn’t. These actions improved the organization of certain areas of the brain. PMFs helped restore normal visual tracking responses and behavior; however, PMFs DIDN’T alter any normal pathways in the mice subjects. Therefore, PMF reorganizes abnormal circuitry without affecting normal connectivity or function.
Additionally, PMFs induced BDNF, GABA and NOS in certain parts of the brain. These substances (as defined below) are beneficial to brain health, mood and stress regulation. This could be one of the ways PEMF helps to counteract the stress response or parts of the sympathetic nervous system.
Brain-derived neurotropic factor (BDNF) – The BDNF gene creates BDNF proteins involved in nerve growth. This protein plays a large role in the survival of striatal neurons, regulating the stress response and mood.
GABA – gamma amino buteryic acid, an inhibitory neurotransmitter that counteracts the sympathetic nervous system, promoting relaxation and even sleep.
NOS – nitric oxide synthase, an enzyme that helps produce nitric oxide, which is important for cell signaling and other functions. It can help with insulin secretion, angiogenesis, and neural development.